EndoSysScore (ESS)
Estimated 30-day mortality after surgery for infective endocarditis
Stacking Ensemble v1.0
1. Demographics
Age (years)
yr
Sex
Male
Female
2. Valve
Valve type
NVE
PVE
Valve involvement (select all that apply)
Aortic
Mitral
Tricuspid
Pulmonary
3. Pathology
Active IE
Abscess
Vegetation
Perforation
Fistula
Pseudoaneurysm
Cerebral embolism
4. Microbiology
S. aureus
Fungal
Streptococci
Enterococci
CoNS
Gram-negative
HACEK
Culture-negative
Polymicrobial
5. Comorbidities
Diabetes
COPD
Hypertension
Obesity
Cirrhosis
Periph. art. disease
Neurological Hx
Dialysis
PAPs > 50 mmHg
CKD stage (0 none to 4 severe)
0
0-None
1
2
3
4-Severe
6. Hemodynamics
Shock
Heart failure
IABP pre-op
Intubation pre-op
LVEF (%)
%
7. Surgery
Urgency
Urgent
Sub-acute
Elective
Number of Redo operations
0
▶︎ Calculate ESS
Estimated 30-day mortality
-
Active Clinical Phenotypes
A: Multi-valve + S.aureus + Renal
B: NVE + Cerebral embolism + Mitral
C: NVE + Age≥80 + LVEF<50
D: NVE + Abscess + Age≥75
Phenotype B: NVE + cerebral embolism (stroke/peripheral) + mitral.
Model Component Probabilities
XGB Shallow
-
XGB Deep
-
Logistic Reg.
-
Meta-LR
-
Platt Cal.
-
ESS v1.0. For research use only. Not validated for routine clinical decision-making without institutional review.